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Drugs that INCREASE Your Risk of Dementia

  • November 7, 2019
    If you are taking any of the Anti-Cholinergics as a long-term medication, then that is exactly what might be happening. You might be taking something to help you sleep or to lessen muscle spasms, and what it might be doing in the background is increasing your risk of developing dementia.

    Here is the list, it is not complete, but contains all the most common drugs:

    Amitriptyline (Elavil) [high AC activity]
    Atropine [high AC activity]
    Benztropine (Cogentin) [high AC activity]
    Chlorpheniramine (Actifed, Chlor-Trimeton, etc.) [high AC activity]
    Chlorpromazine (Thorazine) [high AC activity]
    Clomipramine (Anafranil) [high AC activity]
    Clozapine (Clozaril) [high AC activity]
    Cyclobenzaprine (Amrix, Fexmid, Flexeril) [moderate AC activity]
    Cyproheptadine (Periactin) [moderate AC activity]
    Desipramine (Norpramin) [high AC activity]
    Dexchlorpheniramine (Polaramine) [high AC activity]
    Dicyclomine (Bentyl) [high AC activity]
    Diphenhydramine (Advil PM, Aleve PM, Benadryl, Tylenol PM, Unisom, etc.) [high AC activity]
    Doxepin (Adapin, Silenor, Sinequan) [high AC activity]
    Fesoterodine (Toviaz) [moderate to high AC activity]
    Hydroxyzine (Atarax, Vistaril) [high AC activity]
    Hyoscyamine (Anaspaz, Levbid, Levsin, Levsinex) [high AC activity]
    Imipramine (Tofranil) [high AC activity]
    Meclizine (Antivert, Bonine) [high AC activity]
    Mepenzolate (Cantil) [high AC activity]
    Nortriptyline (Pamelor) [high AC activity]
    Olanzapine (Zyprexa) [high AC activity]
    Orphenadrine (Norflex) [high AC activity]
    Oxybutynin (Ditropan, Oxytrol) [high AC activity]
    Paroxetine (Brisdelle, Paxil) [low AC activity]
    Perphenazine (Trilafon) [high AC activity]
    Prochlorperazine (Compazine) [moderate AC activity]
    Promethazine (Phenergan) [high AC activity]
    Protriptyline (Vivactil) [high AC activity]
    Pseudoephedrine HCl [moderate to high AC activity]
    Scopolamine (Transderm Scop) [high AC activity]
    Thioridazine (Mellaril) [high AC activity]
    Tolterodine (Detrol) [high AC activity]
    Trifluoperazine (Stelazine) [high AC activity]
    Trimipramine (Surmontil) [high AC activity]

    Other drugs which have AC Activity and could pose a risk:
    Alprazolam (Xanax) [low to moderate AC activity]
    Amantadine (Symmetrel) [low AC activity]
    Baclofen [moderate AC activity]
    Brompheniramine [high AC activity]
    Carbamazepine (Tegretol) [moderate AC activity]
    Carbinoxamine (Arbinoxa) [moderate to high AC activity]
    Carisoprodol (Soma) [moderate AC activity]
    Cetirizine (Zyrtec) [moderate AC activity]
    Cimetidine (Tagamet) [moderate AC activity]
    Clemastine (Tavist) [moderate to high AC activity]
    Clidinium & chlordiazepoxide (Librax) [low to moderate AC activity]
    Clorazepate (Tranxene) [low AC activity]
    Codeine [low AC activity]
    Colchicine [low AC activity]
    Darifenacin (Enablex) [moderate to high AC activity]
    Digoxin (Lanoxicaps, Lanoxin) [low AC activity]
    Dimenhydrinate (Dramamine, Gravol, etc) [high AC activity]
    Diphenoxylate/atropine (Lomotil) [moderate to high AC activity]
    Disopyramide (Norpace) [low to moderate AC activity]
    Flavoxate (Urispas) [moderate AC activity]
    Fluphenazine (Prolixin) [moderate AC activity]
    Furosemide (Lasix) [low AC activity]
    Hydrochlorothiazide (Esidrix, Dyazide, HydroDIURIL, Maxzide & others) [low AC activity]
    Loperamide (Imodium) [moderate AC activity]
    Loratadine (Alavert, Claritin) [moderate AC activity]
    Loxapine (Loxitane) [moderate AC activity]
    Maprotiline [low to moderate AC activity]
    Meperidine (Demerol) [moderate AC activity]
    Methocarbamol (Robaxin) [moderate AC activity]
    Methotrimeprazine (Nozinan) [moderate AC activity]
    Nifedipine (Adalat, Procardia) [low AC activity]
    Olanzapine (Zyprexa) [moderate AC activity]
    Orphenadrine (Norflex) [moderate AC activity]
    Quetiapine (Seroquel) [moderate AC activity]
    Procyclidine (Kemadrin) [moderate AC activity]
    Propantheline (Pro-Banthine) [moderate to high AC activity]
    Ranitidine (Zantac) [low AC activity]
    Solifenacin (VESIcare) [low to moderate AC activityy]
    Thiothixene (Navane) [high AC activity]
    Tizanidine (Zanaflex) [high AC activity]
    Tramadol (Ultram) [low AC activity]
    Trihexyphenidyl (Artane) [high AC activity]
    Trospium (Sanctura, Spasmex) [high AC activity]